Availability Develop iOS apps with Xcode for Mac with voiceover and Swift playgrounds 4 for iPad Pro

There is a very similar post I put up a week or so back that might answer some of your questions.

https://www.applevis.com/forum/app-development-programming/learning-code-mac-does-anyone-have-some-suggestions-most-fuss

I did have a quick go at playgrounds on the Mac, the first lessons are simple directions that have to be given in a specific order to move a character around a maze. I suspect that this would work much better on the iPad where there is a touch screen as long as you also have a keyboard. typing in code with either the on screen keyboard or brail screen input would be desperately frustrating.

Someone told me, over on the twitter, that Xcode is having some updates to help with accessibility though, from my understanding, it is a little laborious.

I really hope your new career path goes well. Difficult times indeed.

I can't speak to developing apps on iPad, as I am an iPhone/Mac user.
I can say that I have successfully developed an app on my own with Xcode and VoiceOver, and I am totally blind.
The only part I had trouble with was the icon and I got someone to do it for me, but I am told that this part too can be done if you get someone to draw the base icon.
What would you want your app to do? I think that's the first thing you need to figure out.