The UI control that's present on the Lock Screen when a Focus mode is enabled foes not work as expected when using VoiceOver.
Specifically, turn on a Focus mode and then go to the Lock Screen.
At the bottom centre of the screen is a button that should give access to a dialog where you can disable the Focus Mode.
On some occasions this control can only be located by touch.
On some occasions it has the label “attachment.png, file, Do Not Disturb”.
On some occasions it has the expected label.
In all instances, the control does nothing when double-tapped (or a long press or the pass-through gesture).
In previous iOS releases it would present a dialog that allows you to either turn off the Focus mode or create a new Focus mode.
This control appears to work as expected when VoiceOver is not enabled.